Grey's Anatomy
A Hard Day's Night
Season 1, Episode 1 · Aired 2005-03-27

Synopsis
Meet Meredith Grey, a woman trying to lead a real life while doing a job that makes having a real life impossible. Meredith is a first year surgical intern at Seattle Grace Hospital, the toughest surgical residency program west of Harvard. She and her fellow first-year interns were students yesterday; today they're doctors in a world where on the job training can be a matter of life and death. Meet the young people struggling to become doctors and the doctors struggling to remain human. It's a world filled with intensity, humor, sex and pain, in which the interns discover that neither medicine nor relationships can be defined in black and white -- real life only comes in shades of grey.
From the desk: Grey's Anatomy opens its catalog run with “A Hard Day's Night” (2005-03-27). Longevity, shipping, and soundtrack-driven emotion as brand. Cast exits, on-set controversies, and ship wars without end.
In the series
This episode is part of Grey's Anatomy (2005–present) on ABC.
McDreamy forever — medical soap that refused to leave.
Key cast
- Ellen Pompeo as Meredith Grey
- Sandra Oh as Cristina Yang
- Patrick Dempsey as Derek Shepherd
- Katherine Heigl as Izzie Stevens
- Justin Chambers as Alex Karev
- Chandra Wilson as Miranda Bailey