Grey's Anatomy
Dream a Little Dream of Me (1)
TV Flash files “Dream a Little Dream of Me (1)” as the first listed hour of season 5 — Grey's Anatomy (2005–present) on ABC, season 5, episode 1, aired 2008-09-25, 60 min.
From the desk
How this hour is filed
This leaf is S05E01: listed hour 79 of 467 in the Grey's Anatomy guide, first listed hour of season 5. It aired 2008-09-25 (60 min). The listed hour before it is “Freedom (2)” (S04E17). Next is “Dream a Little Dream of Me (2)” (S05E02). Broadcast log — titles and dates, not a plot bible.

Catalog log
Broadcast listing — not a TV Flash recap.
On the two-hour season premiere of "Grey's Anatomy," Meredith and Derek learn that "happily ever after" isn't easy, a military doctor who brings in a trauma patient catches Cristina's eye, and the Chief and his staff reel at the news that Seattle Grace is no longer nationally ranked as a top-tier teaching hospital.
Viewer FAQ
Where does Dream a Little Dream of Me (1) sit in the Grey's Anatomy guide?
S05E01 is listed hour 79 of 467 — first listed hour of season 5, season 5 episode 1.
When did Grey's Anatomy S05E01 air?
Dream a Little Dream of Me (1) aired 2008-09-25 and is listed at 60 minutes.
Where should I start Grey’s Anatomy?
“A Hard Day’s Night.” The intern-year silhouette is the collection’s first look. Starting at a later “event” is how you miss why the hallway still photographs.
In the series
Why this series still plays
Two decades of scrubs as costume change. Watch it for the way a network medical soap taught America to ship, to soundtrack a trauma, and to treat a hospital hallway like a rope line. It is still on — a season closer is not a finale — and the look keeps getting refitted.
The first flash is intern scrubs under Seattle rain, a look so “casual” it launched a franchise. Ellen Pompeo’s Meredith Grey arrives already in a stolen moment with Patrick Dempsey’s Derek that the publicist would later call a meet-cute and the timeline would call McDreamy — which is to say **this was not a soft launch; this was a hard launch in cotton**. Sandra Oh’s Cristina, Chandra Wilson’s Bailey, the original intern class: a seating chart that became an empire. ABC wanted a medical procedural. Rhimes sent a…
Filed against
- Ellen Pompeo as Meredith Grey
Ellen Pompeo has narrated Grey's Anatomy as Meredith Grey longer than some medical residencies last — McDreamy mythology, cast churn, and soundtrack tears as brand. She became the rare network lead who outlasted eras of TV economics. TV…
- Sandra Oh as Cristina Yang
Sandra Oh’s Cristina Yang made Grey’s Anatomy sound like a surgical dare — Meredith’s person, hallway trauma as a rope line, and Shonda Rhimes teaching network television to ship in scrubs. On TV Flash she is the intern-class steel that…
- Patrick Dempsey as Derek Shepherd
Patrick Dempsey’s Derek Shepherd launched Grey’s Anatomy as a hard launch in cotton — intern scrubs, Seattle rain, and McDreamy as brand architecture. Shonda Rhimes taught network television to ship. TV Flash still treats the hair as a…
- Katherine Heigl as Izzie Stevens
Katherine Heigl’s Izzie Stevens is Grey’s Anatomy vulnerability as tabloid weather — early-season fluorescent glamour, a first-look collection the series later had to survive. Awards talk and gossip in the same corridor. On TV Flash she…
- Justin Chambers as Alex Karev
Justin Chambers’s Alex Karev is Grey’s Anatomy’s long-shift surgeon heat — glamour under fluorescent light, a hospital as a fitting room that never closes. Early-season premiere energy that forgot to end. On TV Flash he is network…
- Chandra Wilson as Miranda Bailey
Chandra Wilson’s Miranda Bailey has ruled Grey’s Anatomy longer than some residencies — Nazi-to-chief evolution, soundtrack tears, and Emmy-winning steel. Longevity as power on Shonda Rhimes’s network medical soap. TV Flash files her…