The Big Bang Theory
The Hofstadter Isotope
Season 2, Episode 20 · Aired 2009-04-13

Synopsis
While a fellow comic book-loving pal of the guys romances Penny, Leonard and Wolowitz venture out into the world of "Ladies' Night" at a local bar.
In the series
This episode is part of The Big Bang Theory (2007–2019) on CBS.
Nerd culture goes multi-cam prime-time global.
Key cast
- Johnny Galecki as Leonard Hofstadter
- Jim Parsons as Sheldon Cooper
- Kaley Cuoco as Penny
- Simon Helberg as Howard Wolowitz
- Kunal Nayyar as Raj Koothrappali
- Mayim Bialik as Amy Farrah Fowler