All episodes Season 5 S05E22 2009-05-07 60 min 2000s ABC

Grey's Anatomy

What a Difference a Day Makes

TV Flash files “What a Difference a Day Makes” as hour 100 of 467 in the TV Flash guide — Grey's Anatomy (2005–present) on ABC, season 5, episode 22, aired 2009-05-07, 60 min.

From the desk

How this hour is filed

This leaf is S05E22: listed hour 100 of 467 in the Grey's Anatomy guide, hour 22 of 24 in season 5. It aired 2009-05-07 (60 min). The listed hour before it is “No Good at Saying Sorry” (S05E21). Next is “Here's to the Future” (S05E23). Broadcast log — titles and dates, not a plot bible.

Grey's Anatomy — What a Difference a Day Makes (S05E22)

Catalog log

Broadcast listing — not a TV Flash recap.

As Meredith, Derek and all of their friends prepare for the big wedding, a group of college students, injured in a car crash as they were heading to their graduation ceremony, is admitted to the ER. Meanwhile, Izzie fears the worst when she begins experiencing familiar symptoms.

Viewer FAQ

Where does What a Difference a Day Makes sit in the Grey's Anatomy guide?

S05E22 is listed hour 100 of 467 — hour 22 of 24 in season 5, season 5 episode 22.

When did Grey's Anatomy S05E22 air?

What a Difference a Day Makes aired 2009-05-07 and is listed at 60 minutes.

Where should I start Grey’s Anatomy?

“A Hard Day’s Night.” The intern-year silhouette is the collection’s first look. Starting at a later “event” is how you miss why the hallway still photographs.

In the series

Why this series still plays

Two decades of scrubs as costume change. Watch it for the way a network medical soap taught America to ship, to soundtrack a trauma, and to treat a hospital hallway like a rope line. It is still on — a season closer is not a finale — and the look keeps getting refitted.

The first flash is intern scrubs under Seattle rain, a look so “casual” it launched a franchise. Ellen Pompeo’s Meredith Grey arrives already in a stolen moment with Patrick Dempsey’s Derek that the publicist would later call a meet-cute and the timeline would call McDreamy — which is to say **this was not a soft launch; this was a hard launch in cotton**. Sandra Oh’s Cristina, Chandra Wilson’s Bailey, the original intern class: a seating chart that became an empire. ABC wanted a medical procedural. Rhimes sent a…

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